Which of the following is NOT TRUE about Shotgun Sequencing?

A、When DNA fragments derived from different chromosomal regions have repeats of the same sequence, they will appear to overlap;
B、When DNA fragments derived from different chromosomal regions have repeats of the same sequence, they should be from the same gene locus. ;
C、In a new whole shotgun approach, Celera Genomics is sequencing both ends of DNA fragments of short (2 kb), medium (10 kb), and long (BAC or >100 kb) lengths;
D、A large number of reads are then assembled by computer