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Comparison of sources, structural features and functions of osteoblasts and osteoclasts

Comparison of sources, structural features and functions of osteoblasts and osteoclasts

发布时间:2025-02-24 10:12:05
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答案:【计分规则】: Osteoblast: derived from Osteoprogenitor cell. Distribution: surface of the forming bone LM: Large, cuboidal or low columnar cell. Round nucleus. Basophilic cytoplasm EM: Fine processes, processes of adjacent cells make contact via gap junctions. Rich in RER, free ribosomes and Golgi complex Function: Synthesize osteoid (unmineralized ECM). Promote calcification of osteoid. Differentiate into osteocytes. Osteoclast: derived from monocyte Distribution: resorption bay (Howship lacuna) LM: Multinuclear large cell, 2~100 nuclei. Acidophilic cytoplasm. Ruffled border EM: Ruffled border: similar to microvilli. Clear zone: a circular zone of cytoplasm around ruffled border, rich in microfilaments. Rich in lysosomes and phagocytic vacuoles. RER, Mit and Gol. Function: dissolve and absorb bone matrix
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